A series of macrocyclic-acyclic ether-ester compounds containing the isoxazole ring has been prepared by treating various dihydroxy compounds with 3,5-isoxazoledicarbonyl chloride. ... Recently many new and interesting cyclic di- and tetra- ester compounds have been prepared to compare the metal complexation properties of synthetic macrocyclic multidentate compounds with those of naturally occurring macrocyclic antibiotics (1-2). In this paper we report the ...