Amino acids. 8. A novel synthesis of. gamma.-carboxy-L-glutamic acid from L-5-oxoproline esters

F Effenberger, W Mueller, R Keller…

Index: Effenberger; Muller; Keller; Wild; Ziegler Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3064 - 3067

Full Text: HTML

Citation Number: 23

Abstract

Discussion Preparation of N-Alkyl-~-5-oxoproline Esters L-5. The N-substituents of the N- alkyl-~-5-oxoprolinates L-5 were selected with regard to their stabilities toward acids so that, on the one hand, they would not be cleaved by the hydrogen chloride formed during the phosgenation or