Host-guest complexation. 42. Preorganization strongly enhances the tendancy of hemispherands to form hemispheraplexes

KM Doxsee, M Feigel, KD Stewart…

Index: Doxsee, Kenneth M.; Feigel, Martin; Stewart, Kent D.; Canary, Jimmy W.; Knobler, Carolyn B.; Cram, Donald J. Journal of the American Chemical Society, 1987 , vol. 109, # 10 p. 3098 - 3107

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Citation Number: 79

Abstract

Abstract: The design and syntheses of four new macrocyclic host compounds (1-4, Chart I) are reported which contain three cyclic urea carbonyls and two anisyl-like oxygens alternately arranged to bind alkali metal or alkylammonium ion guests. The macroring systems are completed with a 1, 3-xylyl bridging unit containing a methoxy in its 2-and a methyl in its 4-position (1, 2) or a 3, 5-dimethylphenyl group in its 2-position (3, 4). Hosts 1- ...