Syntheses of cholesta-5, 7-diene-3. BETA., 25-diol and cholesta-5, 7-diene-1. ALPHA., 3. BETA., 25-triol.

Y Tachibana, S Yokoyama, M Tsuji

Index: Tachibana, Yoji; Yokoyama, Shinji; Tsuji, Masahiro Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 8 p. 2599 - 2603

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Citation Number: 13

Abstract

Adducts of 3β-acetoxy-and 1α, 3β-diacetoxy-23, 24-dinorchola-5, 7-dien-22-al (7 and 14) with 4-phenyl-3H-1, 2, 4-triazole-3, 5-dione prepared by the ozonolysis of the corresponding adducts of ergosteryl acetate and 1α-acetoxyergosteryl acetate were transformed into 22- bromo-3β-tetrahydropyranyloxy-and 22-iodo-1α, 3β-bis (tetrahydropyranyloxy)-23, 24- dinorchola-5, 7-diene (11 and 26). The halide derivatives (11 and 26) were coupled with 2 ...