The pyranoquinone antibiotics are a diverse family produced by various species of Streptomyces. Some members of this family exhibit antifungal activity, anticancer activity, or anticoccidial activity. l Their useful activity has made these compounds attractive synthetic objectives. Recently, total syntheses of nanaomycin D (11, nanaomycin A (2a), kalafungin, frenolicin, deoxyfrenolicin (2b), and the enantiomer of griseusin (3) have been
