Enol ethers and acetals: acylation with dichloroacetyl, acetyl and benzoyl chloride in ionic liquid medium

…, PM Guarda, N Zanatta, HG Bonacorso, MAP Martins

Index: Guarda, Emerson A.; Marzari, Mara R.B.; Frizzo, Clarissa P.; Guarda, Patricia M.; Zanatta, Nilo; Bonacorso, Helio G.; Martins, Marcos A.P. Tetrahedron Letters, 2012 , vol. 53, # 2 p. 170 - 172

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Citation Number: 3

Abstract

Synthesis of 4-alkoxy-1, 1-dichloro-3-alken-2-ones [CHCl2C (O) C (R2) C (R1)-OR, where R, R1, R2= Et, H, H; Me, Me, H; Et, H, Me; Me,–(CH2) 2–; Me,–(CH2) 3–; Et, Et, H; Et, Bu, H; Et, i-Pr, H; Et, i-Bu, H; Me, Ph, H; Me, thien-2-yl, H] from acylation of enol ethers and acetals with dichloroacetyl chloride, in ionic liquid ([BMIM][BF4] or [BMIM][PF6]) is reported. The synthesis of alkenones [R3–C (O) C (R2) C (R1)-OR], where R/R1/R2/R3= Et/H/H/Ph, t-Bu/ ...