Synlett

Synthesis of xantheno [1, 9-cd] azepines: Electrophilic cyclization of carbamates and N-acyliminium ions

A García, E Gómez, D Domínguez

Index: Garcia, Alberto; Gomez, Eduardo; Dominguez, Domingo Synlett, 2004 , # 13 p. 2331 - 2334

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Citation Number: 3

Abstract

Due to the above difficulties, we turned our attention to Banwell's procedure [12] for the Bischler-Napieralski cyclization of carbamates under mild conditions. Since its discovery, this improved cyclization method has been used effectively in the synthesis of a number of isoquinolones, [13] but we know of only one report of its application to the preparation of seven-membered lactams. [14] The carbamate to be cyclized, 8, was prepared from ...