The reactions of a number of nucleophiles with trans-3-methoxyacrylophenone (MeOAcr) and with trans-3-(methylthio) acrylophenone (MeSAcr) in water and methanol have been studied. The reactions of amines produce enamines as the first observable products, and primary amines show simple kinetics: first-order with respect to amine and first-order with respect to the acrylophenone. Piperidine reactions show kinetics which are consistent with ...
