Quinazolines. II. The interaction of 2, 4-dichloroquinazoline in alcohol with salts and bases

NA Lange, FE Sheibley

Index: Lange; Sheibley Journal of the American Chemical Society, 1931 , vol. 53, p. 3867,3870

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Citation Number: 9

Abstract

In a previous communication'it was shown that when 2, 4-dichloroquinazoline was treated with sodium alcoholates in the presence of phenols only the chlorine atom on position 4 was replaced yielding 2-chloro-4-alkoxyquinazolines, the chlorine atom on position 2 remaining unaffected. In attempting to prepare the nitrile of the as yet unknown quinazoline-2, 4- dicarboxylic acid by treatment of dichloroquinazoline with potassium cyanide in alcoholic ...