Tetrahedron

α-Fluorination of β-ketosulfones by Selectfluor™ F–TEDA–BF 4

H Loghmani-Khouzani, MR Poorheravi, MMM Sadeghi…

Index: Loghmani-Khouzani, Hossein; Poorheravi, Mohammad R.; Sadeghi, Majid M.M.; Caggiano, Lorenzo; Jackson, Richard F.W. Tetrahedron, 2008 , vol. 64, # 30-31 p. 7419 - 7425

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Citation Number: 21

Abstract

Attempted fluorination of β-ketosulfides using Selectfluor™ resulted only in the isolation of the corresponding diaryl disulfides, presumed to arise by decomposition of an unstable fluorinated intermediate. However, fluorination of β-ketosulfones using Selectfluor™ under anhydrous conditions does allow the isolation of both mono-and difluorinated products in moderate to good yields.