Green Chemistry

Reduction of aromatic and aliphatic nitro groups to anilines and amines with hypophosphites associated with Pd/C

M Baron, E Métay, M Lemaire, F Popowycz

Index: Baron, Marc; Metay, Estelle; Lemaire, Marc; Popowycz, Florence Green Chemistry, 2013 , vol. 15, # 4 p. 1006 - 1015

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Citation Number: 23

Abstract

The reduction of aromatic and aliphatic nitro groups to anilines and amines is performed with good yield and selectivity in short reaction times. A mixture of sodium hypophosphite and phosphinic acid is used in the presence of a heterogeneous catalyst 2.5 mol% of Pd/C (5%) in a biphasic water/2-MeTHF system.