Journal of medicinal chemistry

Synthesis and antitumor evaluation of selected 5, 6-disubstituted 1 (2) H-indazole-4, 7-diones

GA Conway, LJ Loeffler, IH Hall

Index: Conway, Gregory A.; Loeffler, Larry J.; Hall, Iris H. Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 876 - 884

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Citation Number: 30

Abstract

A series of novel aziridinyl-substituted 1 (2) H-indazole-4, 7-diones and related 1 (2) H- indazole-4, 7-diones was synthesized and tested against Ehrlich ascites carcinoma growth in male CF1 mice. Ten of the test compounds, including two aziridinyl-substituted 1 (2) H- ...