e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Design, Synthesis, and Chemistry of Sterically Nondemanding Primary Bisphosphines1
N Pillarsetty, K Raghuraman, CL Barnes…
Index: Pillarsetty, Nagavarakishore; Raghuraman, Kannan; Barnes, Charles L.; Katti, Kattesh V. Journal of the American Chemical Society, 2005 , vol. 127, # 1 p. 331 - 336
Design and synthesis of chelating bisphosphines functionalized with the smallest chemical unit “H” on the PIII centers ((PH2CH2) 2CHCH2NHPh (4) and (PH2CH2) 2CHCONHPh (5)) are described. Studies demonstrating that no bulky chemical substituents are necessary to offer thermal/oxidative stability to the-PH2 groups in 4 and 5 are described. The H atoms around the PIII centers in 5 (or 4) concur limited/no steric influence, but yet the phosphines ...