e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
1, 3??Dipole mit zentralem S??Atom aus der Umsetzung von Aziden mit Thiocarbonyl??Verbindungen: Eine unerwartete MeS??Wanderung im Abfangprodukt eines ' …
Reaction of PhN, with O-methyl thiobenzoate (Ila) and thioacetate (llc) as well as with the dithio esters llb, d at 80” yields the corresponding imidates and thioimidates 12 (Scheme 3). The formation of 12 is rationalized by a 1, 3-dipolar cycloaddition of the azide and the C= S group followed by successive elimination of N, and S. In the three-component reaction of llb, PhN3, and the sterically crowded thioketone la, 1, 2, 4-trithiolane 13a and 1, 4, 2- ...