Organic letters

Pd-Catalyzed Autotandem C–C/C–C Bond-Forming Reactions with Tosylhydrazones: Synthesis of Spirocycles with Extended π-Conjugation

R Barroso, RA Valencia, MP Cabal, C Valdes

Index: Florentino, Lucia; Aznar, Fernando; Valdes, Carlos Organic Letters, 2012 , vol. 14, # 9 p. 2323 - 2325

Full Text: HTML

Citation Number: 29

Abstract

A new Pd-catalyzed autotandem process is presented by the reaction of tosylhydrazones of cyclic ketones and 2, 2′-dibromobiphenyls and related systems. The process involves cross-coupling with tosylhydrazone followed by an intramolecular Heck reaction and gives