Normal and Abnormal Heme Biosynthesis. 6. Synthesis and Metabolism of a Series of Monovinylporphyrinogens Related to Harderoporphyrinogen. Further Insights …

TD Lash, UN Mani, ASIM Keck…

Index: Jackson, Anthony H.; Lash, Timothy D.; Ryder, David J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 287 - 298

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Citation Number: 7

Abstract

A series of vinylporphyrinogens were prepared to probe the enzyme coproporphyrinogen oxidase (CPO). Six (2-chloroethyl) porphyrins were synthesized from a common dipyrrylmethane via a, c-biladiene intermediates in excellent yields. Subsequent