Tetrahedron Letters

A catalytic approach to the base-promoted reaction of epoxides with activated methylenes

T Angelini, F Fringuelli, D Lanari, F Pizzo, L Vaccaro

Index: Angelini, Tommaso; Fringuelli, Francesco; Lanari, Daniela; Pizzo, Ferdinando; Vaccaro, Luigi Tetrahedron Letters, 2010 , vol. 51, # 12 p. 1566 - 1569

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Citation Number: 26

Abstract

This contribution reports the results obtained in the definition of a catalytic method for the nucleophilic ring opening of epoxides by activated methylenes promoted by a polymer- supported base. The attention has been focused on the use of polymer supported bases and the best results have been obtained by using 4-(dimethylamino) pyridine (PS-DMAP) and 2- tert-butylimino-2-diethylamino-1, 3-dimethyl-perhydro-1, 3, 2-diazaphosphorine both on ...