Rhodium??Catalyzed Addition of Organoboronic Acids to Aldehydes

M Sakai, M Ueda, N Miyaura

Index: Sakai, Masaaki; Ueda, Masato; Miyaura, Norio Angewandte Chemie - International Edition, 1998 , vol. 37, # 23 p. 3279 - 3281

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Citation Number: 317

Abstract

Abstract Highly inert to ionic additions to aldehydes, aryl-and 1-alkenylboronic acids succumb to a catalytic variant mediated by a [Rh (acac)(CO) 2]–diphosphane complex in aqueous phase at 80–95 C to yield secondary alcohols [Eq.(a)]. A key step in the catalytic cycle is the transmetalation between the boron reagent and the rhodium complex. L n= diphosphane (eg 1, 1′-bis (diphenylphosphanyl) ferrocene); R= aryl, 1-alkenyl; R′= ...