e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Atropisomerism in polymers. Screw-sense selective polymerization of isocyanides by inhibiting the growth of one enantiomer of a racemic pair of helices
…, T Harada, AMF Hezemans, W Drenth
Index: Kamer; Cleij; Nolte; Harada; Hezemans; Drenth Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1581 - 1587
Abstract: Isocyanides polymerize under the catalytic activity of Ni (I1) to the corresponding poly (is0cyanides): nRN+= C-E& [RN= C<],. The polymers are of the rigid-rod type, and their molecules have a helical configuration as a result of hindered rotation in their carbon main chains. Upon polymerization, achiral isocyanides generally form a racemic mixture of left- and right-handed helices, whereas in the case of an optically active isocyanide one screw ...