Tetrahedron letters

Microwave oven synthesis of esters promoted by imidazole

T Hirose, BG Kopek, ZH Wang, R Yusa, BW Baldwin

Index: Hirose, Takuji; Kopek, Benjamin G.; Wang, Zhao-Hui; Yusa, Ritsuko; Baldwin, Bruce W. Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1831 - 1833

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Citation Number: 26

Abstract

Using imidazole as promotion agent, primary, secondary and phenolic alcohol compounds were esterified with aliphatic and aromatic carboxylic acid anhydrides. Heating a ternary mixture of alcohol, anhydride and imidazole in an unmodified microwave oven produced esters in low to high yields, depending on the steric bulk of the alcohol.