Amphiphilic/bipolar metallocorroles that catalyze the decomposition of reactive oxygen and nitrogen species, rescue lipoproteins from oxidative damage, and …

…, A Mahammed, B Fuhrman, N Volkova…

Index: Haber, Adi; Mahammed, Atif; Fuhrman, Bianca; Volkova, Nina; Coleman, Raymond; Hayek, Tony; Aviram, Michael; Gross, Zeev Angewandte Chemie - International Edition, 2008 , vol. 47, # 41 p. 7896 - 7900

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Citation Number: 60

Abstract

Accumulating evidence points towards the involvement of reactive oxygen and nitrogen species (ROS and RNS, respectively) in a very wide variety of diseases.[1] The relationship between atherosclerosis and oxidative/nitrosative stress—the imbalance between the desired production of ROS/RNS and the capability of biological systems to detoxify excess amounts thereof—is often analyzed in terms of damage to the cholesterol-transporting ...