Résumé Racemic and optically active α, β-dibenzyl-γ-butyrolactones (of synthetic origin) were hydroxylated in the α position with respect to the carbonyl group, using oxygen in the presence of LHDS. This led to (−)-trachelogenin 1,(−)-nortrachelogenin 2 and (+)-wikstromol 3, whose interesting pharmacological properties were recently described. These natural lignans were correlated to (±)-methyltrachelogenin 12 whose relative structure was ...
