Immunochemical modeling of receptor-ligand reactions. Report II. Reaction of antibodies simulating N-choline receptor recognition with dicholine and dihomocholine …

AA Burkin, VG Zoryan, YL Kruglyak, LN Shitov…

Index: Burkin, A.A.; Zoryan, V.G.; Kruglyak, Yu.L.; Shitov, L.N.; Levkina, M.Z. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 4 p. 320 - 324 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 4 p. 26 - 29

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Abstract

The synthesis of bis-gamma-dimethylaminopropyl ester of lutaric acid and its iodomethylate is described below in the way of an example of this procedure: a solution of 8.2 g (0.05 mol) of glutaric acid dichloroanhydride in i00 ml of ethyl ether was added dropwise to a solution of 12.6 (0.12 mole) of gamma-dimethylaminopropanoi and 11.8 g (0.12 mol) of triethylamine in 200 ml of ethyl ether. The mixture was boiled for 3 h and left overnight. The resultant ...