Radiation-induced reduction of thymidine in aqueous solution: isolation and characterization of a novel dimeric product

S Nishimoto, H Ide, K Nakamichi…

Index: Nishimoto,S.I.; Ide,H.; Nakamichi,K. Journal of the American Chemical Society, 1983 , vol. 105, p. 6740

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Citation Number: 30

Abstract

The radiation chemistry of DNA constituents has been a subject for intensive studies, because the DNA is considered to be one of the most vital targets of ionizing radiation that leads to lethal damage of bacterial and mammalian cells.', 2 It is suggested by a number of workers that radiolyses of pyrimidine bases and related nucleosides in aqueous solution under deaerated conditions give the possible dimeric products3-'as well as those from the ...