Reactions between substituted 1, 2, 4-triazines and ketones were investigated. General procedures for one-pot synthesis of hydrogenated derivatives of such polycyclic systems as benzo [c][1, 2, 4] triazino [1, 6-a][2] azecine,[1, 2, 4] triazino [1, 6-f] phenantridine, and dicyclopenta [b, d] pyrido [1, 2-f][1, 2, 4] triazine are described.