Tetrahedron Letters

(Z)-N-(4-Decenoyl) homoserine lactone, a new quorum-sensing molecule, produced by endobacteria associated with Mortierella alpina A-178

K Kai, K Kasamatsu, H Hayashi

Index: Kai, Kenji; Kasamatsu, Koji; Hayashi, Hideo Tetrahedron Letters, 2012 , vol. 53, # 40 p. 5441 - 5444

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Citation Number: 6

Abstract

N-Acylhomoserine lactones (AHLs) are the conserved quorum-sensing signal molecules in Gram-negative bacteria.(Z)-N-(4-Decenoyl) homoserine lactone (1), a new AHL, was isolated from the culture broth of the fungus Mortierella alpina A-178 harboring bacterial endosymbionts, called endobacteria. The structure and absolute configuration of 1 were elucidated by EI-MS, chemical synthesis, and chiral GC analysis. The compound induced ...