Discovery of an orally bioavailable NK1 receptor antagonist,(2S, 3S)-(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl) amine (GR203040), with potent …

P Ward, DR Armour, DE Bays, B Evans…

Index: Journal of Medicinal Chemistry, , vol. 38, # 26 p. 4985 - 4992

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Citation Number: 60

Abstract

... l2 This important discovery indicates that NK1 antagonists may be useful for the clinical control of emesis experienced 0 1995 American Chemical Society Page 2. 4986 Journal of Medicinal Chemistry, 1995, Vol. 38, No. 26 ...