4x 4Y providing an asymmetric environment at the reacting carbani~ n. z~-~ We now wish to report evidence for such a scheme involving the addition of 2-vinylpyridine (2-VP) to anions 1-3 at-78 OC in THF and sequential methylation according to reaction 1. Previous~~ rk~~,~ had indicated a very highly stereoselective (> 99%) methylation of 4, yielding meso 7. The corresponding methylation in the presence of larger or cryptated and crowned cations had ...
