Abstract In this and the following two papers the synthesis of myxovirescins A 1, A 2 and M 2, 28-membered macrocyclic lactam-lactones with antibiotic acitivity, is described. A retrosynthetic analysis of the myxovirescin family of ca. 30 target molecules leads to a strategy which could be applied to approximately half of them by slight variations of the building blocks used (Schemes 1–3 and following paper). The southeastern part of the ...
![(2S,4S)-2-(tert-butyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid Structure](https://image.chemsrc.com/caspic/007/56209-56-4.png)
![2-t-Butyl-5-propyl-[1,3]dioxolan-4-one Structure](https://image.chemsrc.com/caspic/386/157733-17-0.png)
