Tetrahedron Letters

Synthesis of the peptide moiety of the jamaicamides

A Tanaka, T Usuki

Index: Tanaka, Ayano; Usuki, Toyonobu Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5036 - 5038

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Citation Number: 7

Abstract

The jamaicamides, isolated from cyanobacterium Lyngbya majuscula in Jamaica, are unique mixed polyketide-peptides that are reported to be blockers of the sodium channels. The peptide moiety contains a pyrrolinone ring and a β-methoxy enone functionality. ...

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