Simple chemoenzymatic access to enantiopure pharmacologically interesting (R)-2-hydroxypropiophenones

AS Demir, H Hamamci, O Sesenoglu, F Aydogan…

Index: Tetrahedron Asymmetry, , vol. 12, # 13 p. 1953 - 1956

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Citation Number: 40

Abstract

... Tetrahedron: Asymmetry. Volume 12, Issue 13, 30 July 2001, Pages 1953–1956. ... 2 Cl 2 ); HPLC (Chiralpak AD): R t (R)=13.3 min, R t (S)=11.4 min, 1 H NMR (CDCl 3 ): δ=7.26–7.46 and 7.76–7.91 (m, 4H), 4.96 (q, J=6.9 Hz, 1H), 3.81 (br.s, 1H), 1.42 (d, J=6.9 Hz, 3H); 13 C NMR ...