Abstract The assembly of highly substituted dienes remains a challenge for organic chemistry. This work represents a strategyfor the construction of highly substituted 1, 3- dienes by meansof a Tsuji–Trost cross coupling between α-allenic acetates and organozinc reagents. The reaction is high yielding, and installs a trisubstituted olefin with E/Z selectivities up to 95: 5 favoring the (E) product. A cheap, commercially available ...
