Lipase-mediated deracemization of secondary 1-phenyl-substituted propargylic alcohols of different topology

…, GD Gamalevich, AV Ignatenko, EP Serebryakov…

Index: Vlasyuk; Gamalevich; Ignatenko; Serebryakov; Struchkova Russian Chemical Bulletin, 2004 , vol. 53, # 3 p. 693 - 702

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Citation Number: 3

Abstract

Abstract Acetylation of (±)-1-phenylnon-2-yn-1-ol,(±)-1-phenylhept-1-yn-3-ol, and (±)-1- phenylundec-4-yn-3-ol ((±)-5) in the presence of lipase from Candida cylindracea (CCL) proceeds slowly to give products with ee≤ 20%. The acetates of these alcohols are ...