e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Thermal hetero [3+ 2] cycloaddition of dipolar trimethylenemethane to O-alkyloximes. Straightforward synthetic routes to substituted pyrrolidines and prolines
S Yamago, M Nakamura, XQ Wang…
Index: Journal of Organic Chemistry, , vol. 63, # 5 p. 1694 - 1703
... The Journal of Organic Chemistry. ... Japan. J. Org. Chem. ... solvent. 10 The reaction does not necessarily require rigorous exclusion of moisture or air and does not appear to suffer very much from the presence of organic impurity either. ...