Tetrahedron

Modular synthesis of triaroylbenzene-derived crownophanes

FC Pigge, F Ghasedi, AV Schmitt, MK Dighe, NP Rath

Index: Pigge, F. Christopher; Ghasedi, Fatemeh; Schmitt, Angela V.; Dighe, Mayuri K.; Rath, Nigam P. Tetrahedron, 2005 , vol. 61, # 22 p. 5363 - 5371

Full Text: HTML

Citation Number: 15

Abstract

An isomeric series of homologous crownophanes (ie, macrocycles possessing structural features of crown ethers and cyclophanes) has been prepared via a concise and modular synthetic route. Macrocyclization is achieved in reasonable yield during the course of an enaminone-triggered benzannulation with bis (aryl ethynyl ketone) reaction partners. The crownophanes examined were active alkali cation binding agents in the gas phase, but ...