As mimics of α-amino acids,[1] α-amino phosphonates have great promise as antibacterial [2] and anti-HIV [3] agents as well as protease inhibitors.[4, 5] Consequently, their enantioselective synthesis, in particular by catalytic enantioselective hydrophosphonylation of preformed imines, has attracted considerable interest.[6, 7] Both chiral metal complexes [8] as well as organic catalysts such as Jacobsen s chiral thiourea derivatives,[9] chiral ...
