Palladium??Catalyzed Three??Component Approach to Promazine with Formation of One Carbon–Sulfur and Two Carbon–Nitrogen Bonds

T Dahl, CW Tornøe, B Bang??Andersen…

Index: Dahl, Troels; Tornoe, Christian W.; Bang-Andersen, Benny; Nielsen, Poul; Jorgensen, Morten Angewandte Chemie - International Edition, 2008 , vol. 47, # 9 p. 1726 - 1728

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Citation Number: 76

Abstract

The formation of aromatic carbon–heteroatom bonds has traditionally been achieved by nucleophilic aromatic substitution or by the copper-mediated Ullman reaction.[1] The former type of chemistry is generally limited to activated substrates, whereas the latter often requires prolonged heating in the presence of excess copper salts. The palladium-catalyzed formation of aromatic CÀN bonds,[2] extensively developed by the groups of Hartwig and ...