Carbohydrate research

Synthesis of a di-and a tri-saccharide related to the k-antigen of Klebsiella type 10 and a study of their inhibition in the precipitin reaction

AK Sarkar, AK Ray, N Roy

Index: Sarkar, Arun K.; Ray, Asim K.; Roy, Nirmolendu Carbohydrate Research, 1989 , vol. 190, p. 181 - 190

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Citation Number: 31

Abstract

Abstract Syntheses of methyl 3-O-α-d-galactopyranosyl-α-d-mannopyranoside (10) and methyl 3-O-α-d-galactopyranosyl-2-O-(β-d-glucopyranosyluronic acid)-α-d- mannopyranoside (11) in good yield are described. Both 10 and 11 significantly inhibit antigen-antibody precipitation in the Klebsiella Type 10 immune system. The results provide more evidence for the structure (1) of the antigen from Klebsiella K-10 and its ...