Tetrahedron letters

Silafunctional compounds in organic synthesis. 27.(Isopropoxydimethylsilyl) methyl grignard reagent: A new nucleophilic hydroxymethylating agent for aldehydes and …

K Tamao, N Ishida

Index: Tamao, Kohei; Ishida, Neyoshi Tetrahedron Letters, 1984 , vol. 25, # 38 p. 4245 - 4248

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Abstract

... Please enable JavaScript to use all the features on this page. Tetrahedron Letters. Volume 25, Issue 38, 1984, Pages 4245–4248. ... Nucleophilic hydroxymethylation of aldehydes and ketones has been achieved by the reaction with the (isopropoxydimethylsilyl)methyl Grignard reagent and the subsequent oxidative cleavage of the carbon-silicon bond. References. (1); For part 26 see, K. Tamao and N. Ishida, J. Organomet. Chem., in press. (2); D. Seebach; ...