C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature

BH Lipshutz, S Huang, WWY Leong…

Index: Tissot, Matthieu; Perez Hernandez, Alexandra; Mueller, Daniel; Mauduit, Marc; Alexakis, Alexandre Organic Letters, 2011 , vol. 13, # 6 p. 1524 - 1527

Full Text: HTML

Citation Number: 26

Abstract

... Volume: Page: ... which the coupling occurs, where the precursor halides are used directly in the presence of Zn metal; ie, no prior formation of RZnX is required.(11a, 13). ... Neither organic solvents nor energy in the form of applied heat or cooling need be invested. ...