Bioconjugate chemistry

Investigation of Novel Bis-and Tris-tetraazamacrocycles for use in the Copper-64 (64Cu) radiolabeling of antibodies with potential to increase the therapeutic index for …

M Ramli, SV Smith, LF Lindoy

Index: Morphy, J. Richard; Parker, David; Kataky, Ritu; Eaton, Michael A. W.; Millican, Andrew T.; et al. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1990 , # 4 p. 573 - 585

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Citation Number: 9

Abstract

... Select a Journal or Book ... a higher log K for Cu 2+ and tend to show enhanced selectivity for Cu 2+ over other biological cations (9). Zimmerman et al. ... the 64 Cu 2+ −L complex of the bifunctional ligand was initially formed and then this product was conjugated to the protein ...