Tetrahedron letters

Oxidations of substituted phenols with hypervalent iodine: applications to the phthalide annulation route to anthraquinones

AS Mitchell, RA Russell

Index: Mitchell, Anthony S.; Russell, Richard A. Tetrahedron Letters, 1993 , vol. 34, # 3 p. 545 - 548

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Citation Number: 61

Abstract

Abstract Substituted phenols are oxidized by phenyliodonium diacetate in methanol to yield either cyclohexa-2, 4-or the isomeric 2, 5-dienones depending upon the structure of the phenol. Annulation of these oxidation products with the anion of 3-cyanophthalide affords access to a range of anthraquinones not previously accessible by this route.