Synthesis and antibacterial activity of novel pyridine and pyrazine derivatives obtained from amidoximes

…, A Kędzia, M Wierzbowska, Z Zwolska

Index: Gobis, Katarzyna; Foks, Henryk; Kedzia, Anna; Wierzbowska, Maria; Zwolska, Zofia Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 6 p. 1271 - 1279

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Citation Number: 11

Abstract

Infections caused by Mycobacteria (M. tuberculosis, M. avium, M. kansasaii, M. bovis) are known to express multidrug-resistance toward most chemicals, disinfectants and number of antibiotics and chemotherapeutics as a consequence of single point mutations [1]. This phenomenon is very dangerous especially for HIV-infected individuals because of significantly increased risk of the infection progress to active disease. Other pathogenic ...