Hydrocyanines: a class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo

K Kundu, SF Knight, N Willett, S Lee…

Index: Kundu, Kousik; Knight, Sarah F.; Willett, Nick; Lee, Sungmun; Taylor, W. Robert; Murthy, Niren Angewandte Chemie - International Edition, 2009 , vol. 48, # 2 p. 299 - 303

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Citation Number: 169

Abstract

The development of fluorescent probes for superoxide and the hydroxyl radical is a central problem in the field of chemical biology.[1] Superoxide and the hydroxyl radical play a significant role in a variety of inflammatory diseases, and probes that can detect these reactive oxygen species (ROS) have tremendous potential as medical diagnostics and research tools.[2–6] Fluorescent sensors for superoxide and the hydroxyl radical, such as ...