Synthetic Communications

Enantioselective alkylations of γ-oxo esters

C Agami, F Meynier, T Rizk

Index: Agami, C.; Meynier, F.; Rizk, T. Synthetic Communications, 1987 , vol. 17, # 3 p. 241 - 250

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Citation Number: 8

Abstract

Chiral oxazolidine derivatives of the title compounds are transformed into ester enolates which are diastereo- selectively alkylated. Subsequent hydrolysis leads to optically active a-alkyl y-0x0 esters. ... In recent years, interest has been focused on the ... R - b 1 R = A-Pr c 1 R - cyclohexyl ... CllO COOCH3 I'2O R R' (1) 1 R - Me , R' = Me - b 8 R = Me c 1 R - A-Pr R' = Me 9 I R - cyclohexyl R' = Me 0 1 R - cyclohexyl , R' = CI12CII=CH ... (5) ; R' - Me , R" - H - b ; R' = ...