Synlett

A Simple One-Pot Synthesis of 2-Aryl-5-alkyl-Substituted Oxazoles by Cs2CO3-Mediated Reactions of Aromatic Primary Amides with 2, 3-Dibromopropene

N Yasmin, JK Ray

Index: Yasmin, Nasima; Ray, Jayanta K. Synlett, 2009 , # 17 p. 2825 - 2827

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Citation Number: 3

Abstract

Abstract A simple and efficient method for the synthesis of 2-aryl-5-alkyl-substituted oxazoles has been developed. A series of 2, 5-disubstituted oxazoles were synthesized in a single step by Cs 2 CO 3-mediated reactions of aromatic primary amides with 2, 3-

~90%

~85%

~83%

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