Tetrahedron Letters

Platinum-catalyzed consecutive C–N bond formation-[1, 3] shift of carbamoyl and ester groups

I Nakamura, Y Sato, S Konta, M Terada

Index: Nakamura, Itaru; Sato, Yusuke; Konta, Sayaka; Terada, Masahiro Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2075 - 2077

Full Text: HTML

Citation Number: 35

Abstract

The reaction of ortho-alkynylphenylureas 1 having a carbamoyl group attached to the nitrogen atom proceeded in the presence of catalytic amounts of PtI4, affording corresponding indole-3-carbamides 2 in moderate to high yields. In addition, the platinum- catalyzed cyclization of ortho-alkynylphenyl carbamates 3 afforded corresponding indole-3- carboxylates 4 in good yields. The present reaction proceeds through the intramolecular ...