Fanis in 1979 as a fluorescent probe of micropolarity.'The prodan moiety was attached to thiols and amines in proteins using acrylodan [6-acryloyl-2-(dimethylamino) naphthalene, 12]. 2* 3 The covalently bound chromophore is a fluorescent molecular sensor of the labeled We have been interested in preparing derivatives of prodan and acrylodan to understand the nature of the emissive intramolecular charge-transfer state. The literature synthesis of ...