Tetrahedron

Oxidative nucleophilic substitution: Transformation of alkylboronic derivatives

C Cazorla, E Métay, M Lemaire

Index: Cazorla, Clement; Metay, Estelle; Lemaire, Marc Tetrahedron, 2011 , vol. 67, # 45 p. 8615 - 8621

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Citation Number: 14

Abstract

An efficient amidation reaction is described in this paper. Potassium alkyltrifluoroborate salts can be transforming to amides from nitriles in the presence of copper acetate and boron trifluoride. An extension of this reaction allowed the formation of amines, ethers, and C–C bond.