Versatile Syntheses of Alkynyl-and Substituted Alkynylcyclopropanes: 2-Alkoxyethynylcyclopropanes for the Anellation of Bicyclo [3.3. 0] octane Fragments

…, C Otte, C Puls, J Hain, S Bräse, A de Meijere

Index: Militzer; Schomenauer; Otte; Puls; Hain; Brase; De Meijere Synthesis, 1993 , # 10 p. 998 - 1012

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Citation Number: 34

Abstract

“Determined by gas chromatography. lation; at first eg (E)-5d is liberated with a small amount (~ 1 mol%) of sodium hydroxide in methanol and remo-ved from the mixture after. workup by distillation, then (Z)-5d is obtained after treatment with a considerably larger amount (~ 20 mol%) of sodium hydroxide. Bro-mination and subsequent coupling with propargylmagne-sium bromide of enantiomerically pure enol ethers 1e15 and 11', 17 ...